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How Semaglutide Lowers Blood Sugar

 Understanding the Benefits of Semaglutide for Diabetes Management with Levemir FlexTouch

Semaglutide is renowned for its powerful hypoglycemic effects, making it a top choice for managing diabetes. As a GLP-1 receptor agonist, semaglutide enhances insulin secretion and suppresses glucagon secretion in a glucose-dependent manner by activating the GLP-1 receptor. It also increases glucose uptake in muscle and adipose tissue while inhibiting hepatic glucose production, delays gastric emptying, and suppresses appetite.

Clinical Efficacy of Semaglutide
Numerous clinical studies have confirmed the efficacy of semaglutide, showing it can reduce glycated hemoglobin (HbA1c) by 1.5% to 1.8% in patients with type 2 diabetes. Its hypoglycemic effect surpasses that of liraglutide, exenatide weekly preparations, and sitagliptin.

Regardless of previous treatment methods or diabetes duration, semaglutide can significantly lower HbA1c, especially in patients with higher baseline levels. In domestic studies, 86.1% of patients reached their target HbA1c (<7%) after 30 weeks of treatment with semaglutide 1.0 mg/week.

Advantages of Semaglutide
1. Weight Loss Effect
Semaglutide not only lowers blood sugar but also aids in weight loss. Studies have shown significant weight reduction in diabetic patients using semaglutide. This weight loss is "smart," meaning it is more significant in those with a higher body mass index (BMI) and minimal in non-obese patients. Thus, even patients with a BMI under 25kg/m² can use it safely.

2. Low Risk of Hypoglycemia
The hypoglycemic action of semaglutide is blood sugar-dependent; it works more effectively at higher blood sugar levels and diminishes as blood sugar normalizes. Analyses indicate a very low risk of hypoglycemia among semaglutide users.

3. Cardiovascular Protection
In addition to its hypoglycemic and weight loss benefits, semaglutide offers cardiovascular protection. Similar to other GLP-1 receptor agonists like liraglutide and dulaglutide, semaglutide has been shown to reduce the risk of major adverse cardiovascular events. It lowers the risk of stroke by 39% and significantly reduces cardiovascular risks, making it ideal for patients with type 2 diabetes, cardiovascular disease, obesity, or kidney disease.

Integrating Levemir FlexTouch in Diabetes Management
For patients using Levemir FlexTouch, integrating semaglutide can further enhance diabetes management. The Levemir FlexTouch pen is an easy-to-use insulin delivery system that provides consistent and precise insulin dosing. Combining it with semaglutide's benefits can optimize blood sugar control and overall health outcomes.

Semaglutide, with its hypoglycemic potency, weight loss benefits, and cardiovascular protection, is a superior choice for managing type 2 diabetes. For those using Levemir FlexTouch, combining it with semaglutide can offer a comprehensive approach to diabetes care. As always, consult with healthcare professionals before making any changes to your diabetes management plan.

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